克隆類型 : |
Mouse Monoclonal Antibody |
亞 型 : |
Mouse IgG1 |
免 疫 原 : |
Purified recombinant fragment of PAK2 expressed in E. coli. |
產(chǎn)品描述 : |
PAK2 (P21-activated kinase 2) is a serine/threonine kinase. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene. |
適用物種 : |
H, Mk |
應(yīng)用范圍 : |
WB, IHC, IF |
應(yīng)用說明 : |
WB: 1:500-1:2000; IHC: 1:200-1:1000; IF: 1:200-1:1000 |
別 名 : |
P21; CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6 |
形 態(tài) : |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
保存條件 : |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/pak2-3b5-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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