| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of EP300 expressed in E. coli. |
|
產品描述 ： |
EP300 (E1A binding protein p300) is an adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It is a histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. p300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this protein cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. |
| 適用物種 ： |
H |
|
應用范圍 ： |
WB |
| 應用說明 ： |
WB: 1:500-1:2000;
|
| 別 名 ： |
EP300 protein; p300; KAT3B |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/ep300-7d8a-antibody |
| 標 記 物 ： |
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產品說明 ： |
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