| 克隆類型 ： |
Mouse Monoclonal Antibody |
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亞 型 ： |
Mouse IgG1 |
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免 疫 原 ： |
Purified recombinant fragment of PPARG(aa170-270) expressed in E. coli.
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產(chǎn)品描述 ： |
PPAR-gamma (Peroxisome proliferator-activated receptor gamma) is a nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, PPAR-gamma binds to a promoter element in the gene for acyl-CoA oxidase and activates transcription. PPAR-gamma controls the peroxisomal beta-oxidation pathway of fatty acid and is a key regulator of adipocyte differentiation and glucose homeostasis. PPAR-gamma forms a heterodimer with the retinoic acid receptor RXRA called adipocyte-specific transcription factor ARF6, which leads to a high transcriptional activity. Defects in PPAR-gamma are the cause of familial partial lipodystrophy type 3, a marked loss of subcutaneous fat from the extremities. Defects in PPAR-gamma are also associated with type 2 insulin-resistant diabetes, hypertension, obesity and colon cancer. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
WB |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
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| 別 名 ： |
Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG; NR1C3 |
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形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/pparg-3a4a-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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