| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of BTK expressed in E. coli. |
|
產(chǎn)品描述 ： |
BTK (Tyrosine-protein kinase BTK) is a tyrosine kinase that plays a crucial role in B-cell ontogeny. Defects in BTK are the cause of X-linked agammaglobulinemia (XLA) also known as X-linked agammaglobulinemia type 1 (AGMX1) or immunodeficiency type 1 (IMD1). XLA is a humoral immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Affected boys have normal levels of pre-B-cells in their bone marrow but virtually no circulating mature B-lymphocytes. This results in a lack of immunoglobulins of all classes and leads to recurrent bacterial infections. |
| 適用物種 ： |
H, Mk |
|
應(yīng)用范圍 ： |
E, WB, IHC, IF |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
IHC: 1:200-1:1000;
IF: 1:200-1:1000;
|
| 別 名 ： |
BTK; Tyrosine-protein kinase BTK; Bruton tyrosine kinase; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; AGMX1; ATK; BPK |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/btk-7f12-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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