| 克隆類型 ： |
Mouse Monoclonal Antibody |
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亞 型 ： |
Mouse IgG2b |
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免 疫 原 ： |
Purified recombinant fragment of human PTK6 expressed in E. coli.
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產(chǎn)品描述 ： |
PTK6 (Protein tyrosine kinase 6) is a 451-amino acid protein (~52kDa), may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. PTK6 has been shown to undergo autophosphorylation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. Expressed at low level in some breast tumors, but not in normal breast tissue. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
WB |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
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| 別 名 ： |
Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK; BRK; PTK6 |
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形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/ptk6-2h12-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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