克隆類型 : |
Mouse Monoclonal Antibody |
免 疫 原 : |
Purified recombinant fragment of CIB1 expressed in E. coli. |
產(chǎn)品描述 : |
CIB1 (Calcium and integrin binding 1) is a 191-amino acid protein (~21kDa), belongs to the calcium-binding protein family. CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function. CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R. |
適用物種 : |
H |
應用范圍 : |
WB, IHC |
應用說明 : |
WB: 1:500-1:2000;
IHC: 1:200-1:1000;
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別 名 : |
Calcium and integrin-binding protein 1; CIB; Calcium- and integrin-binding protein; CIBP; Calmyrin; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; SNK-interacting protein 2-28; SIP2-28; CIB; KIP; PRKDCIP; CIB1 |
形 態(tài) : |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
保存條件 : |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/cib1-5a1f-antibody |
標 記 物 : |
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產(chǎn)品說明 : |
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