| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG2a |
|
免 疫 原 ： |
Purified recombinant fragment of human Lck expressed in E. coli. |
|
產(chǎn)品描述 ： |
Lck (Lymphocyte-specific protein tyrosine kinase) is a 509-amino acid protein (~56kDa), belongs to the Src non-receptor tyrosine kinases family. The Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is expressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. Inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
WB |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
|
| 別 名 ： |
SH2B adapter protein 3; Lymphocyte adapter protein; Lymphocyte-specific adapter protein Lnk; Signal transduction protein Lnk; LNK; SH2B3 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/lck-8e5f-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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