| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of Fibulin 5 expressed in E. coli. |
|
產(chǎn)品描述 ： |
FBLN5 (Fibulin 5) is a 448-amino acid multifunctional extracellular matrix protein (~50kDa). It mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:10000; WB: 1:500-1:2000; IHC: 1:200-1:1000 |
| 別 名 ： |
Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Urine p50 protein; UP50; DANCE; FBLN5; EVEC; UP50; ARMD3 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/fibulin-5-3f10-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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