| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of SRA expressed in E. coli. |
|
產(chǎn)品描述 ： |
SRA (Steroid receptor RNA activator 1) is a 237-amino acid protein (~27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
WB, IHC |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
IHC: 1:200-1:1000;
|
| 別 名 ： |
Steroid receptor RNA activator 1; Steroid receptor RNA activator protein; SRAP; SRA1 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/sra-7h1g-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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