| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of KSHV ORF45 expressed in E. coli. |
|
產(chǎn)品描述 ： |
KSHV (Kaposi's sarcoma-associated herpesvirus) belongs to the gamma-2 herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein and it is localized in the cytoplasm of infected cells. Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus-mediated phosphorylation and nuclear translocation of IRF-7. In consequence, ORF45 efficiently inhibited virus-induced production of type I IFN. It was reported that the ORF45 protein was associated with purified virions. |
| 適用物種 ： |
Vs |
|
應用范圍 ： |
WB, ICC |
| 應用說明 ： |
WB: 1:500-1:2000
ICC: 1:200-1:1000
|
| 別 名 ： |
ORF45 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/kshv-orf45-2d4a-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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