| 克隆類型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
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亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr180/Tyr182 of rat p38 MAPK. |
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產(chǎn)品描述 ： |
Mitogen-activated protein kinase p38 alpha (p38 MAPK) responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. P38 MAPK plays a critical role in the production of some cytokines, for example IL-6. P38 MAPK plays a role in stabilization of EPO mRNA during hypoxic stress. p38 MAPK is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
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| 適用物種 ： |
H, B, D, Ck, M, R, Zf, Mk |
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應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:5,000; WB: 1:1,000: IHC: 1:250 |
| 別 名 ： |
p38 MAPK; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAX-interacting-protein 2; MAP kinase MXI2; SAPK2A; MAPK14; p38 |
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形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography on phosphopeptide and nonphosphopeptide. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/p38-mapk-thr180tyr182-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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