| 克隆類型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser515 of rat munc-18. |
|
產(chǎn)品描述 ： |
Syntaxin-binding protein 2 (Munc-18) is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Munc-18 contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Munc-18 regulates cytotoxic granule exocytosis in natural killer (NK) cells. The function of Munc-18 is regulated by PKC phosphorylation of Ser515. |
| 適用物種 ： |
R, B, D, Ck, H, M, X, Mk |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:1,000; WB: 1:1,000; IHC: 1:400 |
| 別 名 ： |
Syntaxin-binding protein 2; Protein unc-18 homolog 2; Munc18-2; Unc18-2; Protein unc-18 homolog B; Unc-18B |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/munc-18-ser515-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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