| 克隆類型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser311/Thr315 of rat MEK5. |
|
產(chǎn)品描述 ： |
Dual specificity mitogen-activated protein kinase kinase 5 (MEK5) acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway plays a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation. |
| 適用物種 ： |
B, D, Ck, H, M, X, Zf, R, Mk |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:1,000; WB: 1:1,000 |
| 別 名 ： |
MAPKK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK1; MAP2K1; PRKMK3 |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/mek5-ser311thr315-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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