| 克隆類型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser218/222 of human MEK1/2. |
|
產(chǎn)品描述 ： |
Dual specificity mitogen-activated protein kinase kinase 1 (MEK1/2) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1/2 activates ERK1 and ERK2 MAP kinases. Defects in MEK1/2 are a cause of cardiofaciocutaneous syndrome (CFC syndrome), also known as cardio-facio-cutaneous syndrome. CFC syndrome is characterized by distinctive facial appearance, heart defects and mental retardation. |
| 適用物種 ： |
B, D, Ck, H, R, X, Zf |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說(shuō)明 ： |
E: 1:1,000; WB: 1:1,000 |
| 別 名 ： |
MEK1/2; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K1; MEK1; PRKMK1 |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/mek12-ser218222-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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