| 克隆類型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
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亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser535/539 of human interferon-a receptor, type I, subunit I. |
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產(chǎn)品描述 ： |
Interferon-a Receptor, Type I, Subunit I (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. This interferon receptor is a receceptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Down regulation of IFNAR1 is influenced by phosphorylation of Serine 535 and 539.
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| 適用物種 ： |
B, D, H, M, Sh, R, Mk |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
MW of phosphorylated IFNAR1 is observed at 110-130 kDa depending on cell lines due to different glycosylation patterns. E: 1:1,000; WB: 1:1,000; IHC: 1:1,000 |
| 別 名 ： |
Interferon alpha/beta receptor 1; FN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1 Type I interferon receptor 1; IFNAR1; IFNAR |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/ifnar1-ser535539-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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