| 克隆類型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser9 of rat glycogen synthase kinase 3 B (GSK3B). |
|
產(chǎn)品描述 ： |
Glycogen synthase kinase-3 beta (GSK3b) participates in the Wnt signaling pathway. GSK3b is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor Jun. GSK3b phosphorylates Jun at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Ser9 phosphorylation underlies the inhibition of GSK3b by insulin. This antibody is specific for the 46-kDa GSK-3b protein phosphorylated at Ser9, however a band at 51-kDa can also be detected due to high homology with GSK-3 alpha. |
| 適用物種 ： |
H, M, Ck, B, D, Zf, X, Mk |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:1,000; WB: 1:1,000 |
| 別 名 ： |
Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/gsk3b-ser9-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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