| 克隆類型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
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亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser880 of rat GluR2-subunit. |
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產(chǎn)品描述 ： |
The glutamate receptor 2, a homo- or heter0teramer, is an Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Ser880 has been identified as a PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1.
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| 適用物種 ： |
H, M, R, Zf, Ck |
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應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:1,000; WB: 1:1,000 |
| 別 名 ： |
Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2; Gria2; Glur2 |
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形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/glur2-ser880-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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