| 克隆類型 ： |
Sheep Polyclonal Antibody, Phosphospecific Antibody |
|
亞 型 ： |
Sheep Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser774 of rat dynamin. |
|
產(chǎn)品描述 ： |
Dynamin-1 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin-1 is involved in vesicular trafficking processes, and is involved in receptor-mediated endocytosis. Phosphorylation of Ser774 by GSK3 has been shown to control activity-dependent bulk endocytosis of synaptic vesicles. This antibody is specific for the 95-kDa dynamin protein phosphorylated at Ser774. The antibody detects purified Dynamin phosphorylated in vitro by CdK5 but not by PKC. The antibody does not cross-react with other proteins subtrates of Cdk5 such as amphiphysin and synapsin. |
| 適用物種 ： |
B, D, Ck, H, M, R, Mk |
|
應(yīng)用范圍 ： |
E, WB, IF, IHC |
| 應(yīng)用說明 ： |
E: 1:1,000; WB: 1:1,000; IHC: 1,1000; IF: 1:1,000 |
| 別 名 ： |
Dynamin-1; DNM1; DNM |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/dynamin-ser774-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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