克隆類型 : |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser490/498 of rat ATF2. |
產(chǎn)品描述 : |
Activating transcription factor 2 (ATF2) is a transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) consensus sequence: 5'-GTGACGT[AC][AG]-3', a sequence present in many viral and cellular promoters. ATF2 binds DNA as a dimer and can form a homodimer in the absence of DNA. ATF2 can form a heterodimer with JUN, and interacts with SMAD3 and SMAD4. Stress induced ATF-dependent transcription is dependent on phosphorylation of ATF. |
適用物種 : |
R, H |
應(yīng)用范圍 : |
E, WB, IHC |
應(yīng)用說明 : |
E: 1:1,000; WB: 1:1,000; IHC: 1:1,000 |
別 名 : |
ATF-2; Activating Transcription Factor 2; ATF2; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16; Cyclic AMP-responsive element-binding protein 2; cAMP-responsive element-binding protein 2; CREB-2; CREB2; CREBP1 |
形 態(tài) : |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/atf2-ser490498-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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