克隆類型 : |
Rabbit Polyclonal Antibody, HRP-conjugated Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD167a. |
產(chǎn)品描述 : |
DDR1 (Epithelial discoidin domain-containing receptor 1, CD167a) is a receptor tyrosine kinase involved in cell-cell interactions and recognition. It is expressed in epithelial cells especially in the kidney, lung, gastrointestinal tract, and brain, and more highly in human breast, ovarian, esophageal, and pediatric brain tumors. Types I-VI collagen all induce the autophosphorylation of DDR1. Collagen regulates the interaction of DDR1 with KIBRA (WWC1), activating MAPK; these events are involved in mammary gland development. |
適用物種 : |
H, M, R |
應(yīng)用范圍 : |
E, WB, IHC |
應(yīng)用說(shuō)明 : |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
別 名 : |
Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; Tyrosine kinase DDR; Discoidin receptor tyrosine kinase; Tyrosine-protein kinase CAK; Cell adhesion kinase; TRK E; Protein-tyrosine kinase RTK 6; CD167a antigen; HGK2; DDR1; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA and 0.02% gentamicin. Antibody was purified by Protein-G affinity chromatography. |
保存條件 : |
Store at -20°C. Product is guaranteed 6 months from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/cd167a-ddr1-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說(shuō)明 : |
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