| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human HERG. |
|
產(chǎn)品描述 ： |
Potassium voltage-gated channel subfamily H member 2 (HERG) is the pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. The HERG channel properties are modulated by cAMP and subunit assembly. HERG mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1. Defects in HERG are the cause of long QT syndrome type 2 (LQT2). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:1,000-1:10,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
Potassium voltage-gated channel subfamily H member 2; Voltage-gated potassium channel subunit Kv11.1; Ether-a-go-go-related gene potassium channel 1; Ether-a-go-go-related protein 1; Eag-related protein 1; ERG-1; hERG-1; hERG1; H-ERG; Eag homolog; KCNH2; ERG; ERG1; HERG |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/herg-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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