| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human STUB1. |
|
產品描述 ： |
STIP1 homology and U box-containing protein 1 (STUB1) is an ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. STUB1 ubiquitinates NOS1 in concert with Hsp70 and Hsp40. STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. STUB1 mediates polyubiquitination of CYP3A4. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:4,000-1:50,000; WB: 1:200-1:1,000; IHC: 1:50-1:200 |
| 別 名 ： |
STIP1 homology and U box-containing protein 1; Carboxy terminus of Hsp70-interacting protein; E3 ubiquitin-protein ligase CHIP; CLL-associated antigen KW-8; Antigen NY-CO-7; STUB1; CHIP |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/stub1-antibody |
| 標 記 物 ： |
|
|
產品說明 ： |
|
