克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within human FXR. |
產(chǎn)品描述 : |
Bile acid receptor (FXR) is a ligand-activated transcription factor. FXR is a receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. FXR represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression via two distinct mechanisms. FXR activates the intestinal bile acid-binding protein (IBABP). FXR activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus. |
適用物種 : |
H, M, R |
應(yīng)用范圍 : |
E, WB |
應(yīng)用說明 : |
E: 1:1,000-1:5,000; WB: 1:100-1:500 |
別 名 : |
Bile acid receptor; Farnesoid X-activated receptor; Farnesol receptor HRR-1;
Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor-interacting protein 14; RXR-interacting protein 14
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形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/fxr-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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