| 克隆類(lèi)型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse p47-phox. |
|
產(chǎn)品描述 ： |
p47-phox (NCF1) interacts with NCF2 and cytochrome b558 for activation of NADPH oxidase, which is required for superoxide production. Defects in p47-phox are linked to chronic granulomatous disease, a genetic disorder characterized by the inability of neutrophils and phagocytes to kill microbes they have ingested. Patients can suffer from life-threatening bacterial or fungal infections. |
| 適用物種 ： |
M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC, IF |
| 應(yīng)用說(shuō)明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IF: 1:100-1:500 |
| 別 名 ： |
Neutrophil cytosol factor 1; NCF-1; Neutrophil NADPH oxidase factor 1; 47 kDa neutrophil oxidase factor; p47-phox; NCF-47K; 47 kDa autosomal chronic granulomatous disease protein; Nox-organizing protein 2; Nox organizer 2; SH3 and PX domain-containing protein 1A; NCF1; NOXO2; SH3PXD1A |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Kim J et al. 2013. PLoS ONE. 8(9):e74458. PMID# 24040253 |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/p47-phox-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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