克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human nucleophosmin. |
產(chǎn)品描述 : |
Nucleophosmin is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. Nucleophosmin binds ribosomes presumably to drive ribosome nuclear export. Nucleophosmin associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. Nucleophosmin acts as a chaperonin for the core histones H3, H2B and H4. A chromosomal aberration in nucleophosmin is found in a form of non-Hodgkin lymphoma. |
適用物種 : |
H, M, R |
應(yīng)用范圍 : |
E, WB, IHC |
應(yīng)用說明 : |
E: 1:10,000-1:50,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
別 名 : |
Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Numatrin; Nucleolar protein NO38; NPM1; NPM |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/nucleophosmin-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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