| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CREB-1. |
|
產(chǎn)品描述 ： |
Cyclic AMP-responsive element-binding protein 1 (CREB-1) is a protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB-1 stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 is implicated in synchronization of circadian rhythmicity. Defects in CREB-1 have been implicated in angiomatoid fibrous histiocytoma (AFH), a distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:10,000-1:40,000; WB: 1:100-1:500; IHC: 1:50-1:50 |
| 別 名 ： |
Cyclic AMP-responsive element-binding protein 1; cAMP-responsive element-binding protein 1; CREB-1; CREB1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/creb-1-antibody-1 |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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