| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human KLF8. |
|
產(chǎn)品描述 ： |
Krueppel-like factor 8 (KLF8) is a transcriptional repressor and activator. KLF8 binds to CACCC-boxes promoter elements. KLF8 also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G1 phase as a downstream target of focal adhesion kinase (FAK). Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G1 phase. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:10,000-1:50,000; WB: 1:200-1:1,000 |
| 別 名 ： |
Krueppel-like factor 8; Basic krueppel-like factor 3; Zinc finger protein 741; KLF8; BKLF3; ZNF741 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻 ： |
Wang J et al. 2015. Oncol Lett. 9(6): 2515-9. PMID 26137099. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/klf8-antibody |
| 標 記 物 ： |
|
|
產(chǎn)品說明 ： |
|
