| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ICSBP. |
|
產(chǎn)品描述 ： |
Interferon regulatory factor 8 (ICSBP) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). ICSBP plays a negative regulatory role in cells of the immune system. ICSBP is ubiquitinated by TRIM21 in macrophages, a process that is strongly increased upon interferon gamma stimulation. This leads to the enhanced transcriptional activity of target cytokine genes. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:10,000-1:50,000; WB: 1:200-1:1,000 |
| 別 名 ： |
Interferon regulatory factor 8; IRF-8; Interferon consensus sequence-binding protein; ICSBP; IRF8; ICSBP1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/icsbp-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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