| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PPP6C. |
|
產品描述 ： |
Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C A) is the catalytic subunit of protein phospatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PP6C A restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PP6C A downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. PP6C A is ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB |
| 應用說明 ： |
E: 1:10,000-1:50,000; WB: 1:500-1:2,000 |
| 別 名 ： |
Serine/threonine-protein phosphatase 6 catalytic subunit; PP6C; PPP6C; PPP6 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/pp6c-antibody |
| 標 記 物 ： |
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產品說明 ： |
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