| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human APBA1. |
|
產(chǎn)品描述 ： |
Amyloid beta A4 precursor protein-binding family A member 1 (APBA1) functions in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. APBA1 modulates processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. APBA1 is composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:10,000-1:50,000; WB: 1:100-1:1,000 |
| 別 名 ： |
Amyloid beta A4 precursor protein-binding family A member 1; Neuron-specific X11 protein; Neuronal Munc 18-1-interacting protein 1; Mint-1; Adapter protein X11alpha; APBA1; MINT1; X11 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/apba1-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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