| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PDCD4. |
|
產(chǎn)品描述 ： |
Programmed cell death protein 4 (PDCD4) inhibits translation initiation and cap-dependent translation. PDCD4 excerts its function by hindering the interaction between EIF4A1 and EIF4G. PDCD4 inhibits the helicase activity of EIF4A and modulates the activation of JUN kinase. PDCD4 down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription.PDCD4 inhibits tumor promoter-induced neoplastic transformation. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說(shuō)明 ： |
E: 1:10,000-1:50,000; WB: 1:100-1:1,000; IHC: 1:100-1:500 |
| 別 名 ： |
Programmed cell death protein 4; Nuclear antigen H731-like; Neoplastic transformation inhibitor protein; Protein 197/15a; PDCD4; H731 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/pdcd4-antibody |
| 標(biāo) 記 物 ： |
|
|
產(chǎn)品說(shuō)明 ： |
|
