| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ANG2. |
|
產(chǎn)品描述 ： |
Angiopoietin-2 (ANG2) induces tyrosine phosphorylation of TIE2. ANG2 binds to the TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. ANG2 function is context-dependent: In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, ANG2 facilitates endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:5,000-1:20,000; WB: 1:100-1:500; IHC: 1:50-1:200 |
| 別 名 ： |
ANGPT2; Angiopoietin-2; ANG-2; ANG2 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/ang2-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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