| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human AMPK alpha-2. |
|
產(chǎn)品描述 ： |
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 Antibody) is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. AMPK alpha-2 regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. AMPK alpha-2 acts as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說(shuō)明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500 |
| 別 名 ： |
5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; PRKAA2; AMPK; AMPK2 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/ampk-alpha-2-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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