| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GW182. |
|
產(chǎn)品描述 ： |
Trinucleotide repeat-containing gene 6A protein (GW182) plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). GW182 is required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. Antibodies against GW182 are found in sera from patients with Sjoegren syndrome (SS), ataxia and sensor neuropathy diseases that developed autoantibodies against protein of the GWB structure. Autoantibodies were mapped to the GW-rich mid-part, the non-GW-rich region and the C-terminus of the protein. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:1,000-1:10,000; WB: 1:100-1:500 |
| 別 名 ： |
Trinucleotide repeat-containing gene 6A protein; CAG repeat protein 26; Glycine-tryptophan protein of 182 kDa; GW182 autoantigen; Protein GW1; EMSY interactor protein; TNRC6A; CAGH26; KIAA1460; TNRC6 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/gw182-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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