| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AKR1A1. |
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產(chǎn)品描述 ： |
Alcohol dehydrogenase [NADP+] (AKR1A1) catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. AKR1A1 catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. AKR1A1 has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. AKR1A1 plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:1,000-1:10,000; WB: 1:100-1:1,000; IHC: 1:50-1:500 |
| 別 名 ： |
Alcohol dehydrogenase [NADP+]; Aldehyde reductase; Aldo-keto reductase family 1 member A1; AKR1A1; ALDR1; ALR |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/akr1a1-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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