| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ADAM 15. |
|
產(chǎn)品描述 ： |
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) is a metalloproteinase with gelatinolytic and collagenolytic activity. ADAM 15 plays a role in the wound healing process, mediating both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. ADAM 15 inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. ADAM 15 suppresses cell motility towards fibronectin by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. ADAM 15 cleaves E-cadherin in response to growth factor deprivation. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:10,000-1:50,000; WB: 1:200-1:1,000; IHC: 1:100-1:500 |
| 別 名 ： |
Disintegrin and metalloproteinase domain-containing protein 15; ADAM 15; Metalloproteinase-like, distegrin-like, and cysteine-rich protein 15; MDC-15; Metalloprotease RGD disintegrin protein; Metargidin; ADAM15; MDC15 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/adam-15-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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