| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ABCE1. |
|
產(chǎn)品描述 ： |
ATP-binding cassette sub-family E member 1 (ABCE1) antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. ABCE1 plays a central role in the regulation of mRNA turnover. ABCE1 antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway, an acts as a chaperone for post-translational events during HIV-1 capsid assembly. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說(shuō)明 ： |
E: 1:10,000-1:50,000; WB: 1:500-1:1,000 |
| 別 名 ： |
ATP-binding cassette sub-family E member 1; RNase L inhibitor; Ribonuclease 4 inhibitor; RNS4I; 2'-5'-oligoadenylate-binding protein; HuHP68; ABCE1; RLI; RNASEL1; RNASELI; RNS4I |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/abce1-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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