克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the center egion of human DR-5. |
產(chǎn)品描述 : |
HLA class II histocompatibility antigen, DRB1-5 beta chain (DR-5) is a heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. DR-5 binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases. |
適用物種 : |
H |
應(yīng)用范圍 : |
E, WB, IHC |
應(yīng)用說(shuō)明 : |
E: 1:10,000-1:40,000; WB: 1:100-1:1,000 |
別 名 : |
HLA class II histocompatibility antigen, DRB1-11 beta chain; MHC class II antigen DRB1*11; DRw11; DR-5; DR5; HLA-DRB1 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/dr-5-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說(shuō)明 : |
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