| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DR-4. |
|
產(chǎn)品描述 ： |
HLA class II histocompatibility antigen, DRB1-4 beta chain (DR-4) is a heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. DR-4 binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accomodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:10,000-1:50,000; WB: 1:100-1:1,000 |
| 別 名 ： |
HLA class II histocompatibility antigen, DRB1-4 beta chain; MHC class II antigen DRB1*4; DR-4; DR4; HLA-DRB1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/dr-4-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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