| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PARP-14. |
|
產(chǎn)品描述 ： |
Poly [ADP-ribose] polymerase 14 (PARP-14) functions as a transcriptional switch for Stat6-dependent gene induction. In the absence of a signal, PARP-14 acts as a transcriptional repressor by recruiting histone deacetylases (HDACs). In contrast, in the presence of IL-4 the catalytic activity of PARP-14 facilitates Stat6 binding to the promoter, and release of HDACs so as to activate transcription. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:10,000-1:40,000; WB: 1:100-1:500 |
| 別 名 ： |
Poly [ADP-ribose] polymerase 14; PARP-14; B aggressive lymphoma protein 2; PARP14; BAL2; KIAA1268 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/parp-14-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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