| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Caspase-3. |
|
產品描述 ： |
Caspase-3 (CASP-3) is involved in the activation of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase-3 cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase-3 cleaves and activates caspase-6, -7 and -9, and is involved in the cleavage of huntingtin. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:10,000-1:50,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
Caspase-3; CASP-3; Apopain; Cystein protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; CASP3; CPP32 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.2, with 0.02% sodium azide, 0.5% BSA. Antibody was antigen affinity purified. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/caspase-3-antibody-0 |
| 標 記 物 ： |
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產品說明 ： |
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