| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Pax-6. |
|
產品描述 ： |
Paired box protein (Pax-6) is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Pax-6 is required for the differentiation of pancreatic islet alpha cells, and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Pax-6 regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Defects in Pax-6 are associated with a number of diseases and abnormalities of the eye and optic nerve. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB |
| 應用說明 ： |
E: 1:10,000-1:50,000; WB: 1:100-1:1,000 |
| 別 名 ： |
Paired box protein Pax-6; Oculorhombin; Aniridia type II protein; PAX6; AN2 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產品文獻 ： |
Li W et al. 2012. Invest Opthalmol Vis Sci. 50:5334-5343. PMID# 22736612. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/pax-6-antibody |
| 標 記 物 ： |
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產品說明 ： |
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