| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BIGH3. |
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產(chǎn)品描述 ： |
Transforming growth factor-beta-induced protein ig-h3 (BIGH3) binds to type I, II, and IV collagens. BIGH3 plays a role in cell-collagen interactions. In cartilage, BIGH3 is involved in endochondral bone formation. Defects in BIGH3 are the cause of epithelial basement membrane corneal dystrophy (EBMD), also known as Cogan corneal dystrophy or map-dot-fingerprint type corneal dystrophy. EBMD is a bilateral anterior corneal dystrophy characterized by grayish epithelial fingerprint lines, geographic map-like lines, and dots (or microcysts) on slit-lamp examination. Pathologic studies show abnormal, redundant basement membrane and intraepithelial lacunae filled with cellular debris. Although this disorder usually is not considered to be inherited, families with autosomal dominant inheritance have been identified.
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| 適用物種 ： |
H, M |
|
應用范圍 ： |
E, WB |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500 |
| 別 名 ： |
Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP; TGFBI; BIGH3 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/bigh3-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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