| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Smad2/3. |
|
產(chǎn)品描述 ： |
SMAD family member 2 (SMAD2/3) is receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. SMAD2/3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. SMAD2/3 acts as a tumor suppressor in colorectal carcinoma. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
SMAD2; Mothers against decapentaplegic homolog 2; Mothers against DPP homolog 2; Mad-related protein 2; hMAD-2; MADH2; MADR2; SMAD3; Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; hMAD-3; SMAD family member 3; Smad3; hSMAD3; JV15-2; SMAD3; MADH3 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻 ： |
Hae-Young L et al. 2013. Elsevier. The American Journal of Pathology. doi:10.1016/j.ajpath.2013.02.009. PMID# 23684430. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/smad23-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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