| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human integrin alpha-4. |
|
產(chǎn)品描述 ： |
Integrin alpha-4 (CD49d) is a receptor for fibronectin. Integrin alpha-4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-4 is also a receptor for VCAM1, recognizing the sequence Q-I-D-S in VCAM1, and a receptor for MADCAM1, recognizing the sequence L-D-T in MADCAM1. On activated endothelial cells, integrin alpha-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines, and also participates in cytolytic T-cell interactions with target cells. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC, ICC |
| 應(yīng)用說(shuō)明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:200; ICC: 1:50-1:100, in acetone fixed cells, antigen retrieval with pepsin and trypsin is recommended. |
| 別 名 ： |
Integrin alpha-4; Integrin alpha-IV; VLA-4 subunit alpha; CD49 antigen-like family member D; CD49d; ITGA4; CD49D |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.5 ml (0.2 mg/ml) of PBS pH7.4, 50% glycerol. Antibody was purified by immunogen-affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Prisco AR et al. 2014. Am J Physiol Heart Circ Physiol. PMID#25539711. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/alpha-4-integrin-antibody |
| 標(biāo) 記 物 ： |
|
|
產(chǎn)品說(shuō)明 ： |
|
|
