| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BAX. |
|
產(chǎn)品描述 ： |
Apoptosis regulator BAX (BAX or Bcl-2-like protein 4) accelerates programmed cell death by binding to and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX induces the release of cytochrome c, activation of caspase-3 and apoptosis. BAX forms heterodimers with BCL2, Bcl-X(L), MCL1 and A1 by interacting with BH3 domains in BIK, BID, BAK, and BAD. Defects in BAX are found in some cell lines from hematopoietic malignancies. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500 |
| 別 名 ： |
Bax; Bcl-2 associated X protein; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl-2-like protein 4; Bcl2-L-4; BAX; BCL2L4 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Wu Q et al. Journal of Ethnopharmacology. 2011. doi:10.1016/j.jep.2011.08.009 |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/bax-antibody-1 |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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