| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
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免 疫 原 ： |
BSA-conjugated synthetic peptide containing the evolutionarily conserved PSTAIR sequence. |
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產(chǎn)品描述 ： |
The cell cycle is controlled in part by cyclin dependent kinases (CDKs) which are themselves controlled by modifications such as phosphorylation of CDKs and formation of complex(es) with other proteins, including the cyclins. CDKs are key regulators of cell cycle progression. CDKs are closely related in size (35-40 kD) and sequence (>40% identity) and associate with and are activated by a cyclin which acts as a regulatory subunit. In every eukaryote examined, CDKs contain an evolutionary conserved 16 amino acid sequence called PSTAIR (EGVPSTAIREISLLKE) which distinguishes them from other protein kinases. The PSTAIR motif is involved in the complex formation with cyclins. The availability of antibodies reacting specifically with the PSTAIR sequence enables the subcellular detection and localization of the various CDKs and examination of substrate interactions, in a variety of organisms. |
| 適用物種 ： |
H, M, R, Zf, X, Hm, Ck |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500 |
| 別 名 ： |
PSTAIR; CDK; CDC; Cyclin-dependent kinase; Cell division protein kinase; Cell division control protein |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/pstair-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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