| 克隆類(lèi)型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Human milk fat globule membranes. |
|
產(chǎn)品描述 ： |
CA15-3 (MUC-1) is a type I transmembrane protein expressed in the apical membrane of highly polarized epithelial cells. CA15-3 is also overexpressed in epithelial tumors, such as breast or ovarian cancer. CA15-3 is composed of alpha and beta subunits. The alpha subunit has cell adhesive properties, whereas the beta subunit modulates signaling in the SRK, ERK, and NF-kappa B pathways. CA15-3 is used as a serological clinical marker of breast cancer to monitor response to breast cancer treatment and disease recurrence. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, IHC |
| 應(yīng)用說(shuō)明 ： |
IHC: 1:100-1:500; E: 1:500-1:1,000 |
| 別 名 ： |
CA15-3; CA15.3; CA153; Carbohydrate antigen 15-3; Cancer antigen 15-3; Mucin-1; MUC-1; Polymorphic epithelial mucin; PEM; PEMT; Episialin; Tumor-associated mucin; Carcinoma-associated mucin; Carcinoma-associated mucin; Tumor-associated epithelial membrane antigen; EMA; H23AG; Peanut-reactive urinary mucin; PUM; Breast carcinoma-associated antigen DF3; CD227; MUC1; PUM; Krebs von den Lungen-6; KL-6 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/mucin-1-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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