| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG2a |
|
免 疫 原 ： |
Human liver cathepsin D. |
|
產(chǎn)品描述 ： |
Cathepsin D is an acid protease active in intracellular protein breakdown. Cathepsin D is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Cathepsin D consists of a light chain and a heavy chain. Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10), also known as neuronal ceroid lipofuscinosis due to cathepsin D deficiency. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material. This results in seizures, dementia, visual loss, and/or cerebral atrophy. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說(shuō)明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500 |
| 別 名 ： |
Cathepsin D; CTSD; CPSD |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Rouse R et al. 2013.Toxicologic Pathology. doi: 10.1177/0192623313486967. PMID# 23640381. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cathepsin-d-antibody |
| 標(biāo) 記 物 ： |
|
|
產(chǎn)品說(shuō)明 ： |
|
