克隆類型 : |
Mouse Monoclonal Antibody |
亞 型 : |
Mouse IgG2b |
免 疫 原 : |
Recombinant polypeptide encompassing the center region of human BIN1. |
產(chǎn)品描述 : |
Box-dependent myc-interacting protein 1 (BIN1) is involved in regulation of synaptic vesicle endocytosis. BIN1 acts as a tumor suppressor and inhibits malignant cell transformation. Defects in BIN1 are the cause of centronuclear myopathy autosomal recessive (ARCNM), also known as autosomal recessive myotubular myopathy. Centronuclear myopathies are congenital muscle disorders characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. |
適用物種 : |
H, M, R |
應(yīng)用范圍 : |
E, WB, IHC; ICC |
應(yīng)用說明 : |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500 |
別 名 : |
BIN1; Myc box-dependent-interacting protein 1; Bridging integrator 1; Amphiphysin-like protein; Amphiphysin II; Box-dependent myc-interacting protein 1; AMPHL |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/bin1-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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